FNTA

Across TCGA patient cohorts, FNTA protein abundance is significantly associated with the RNA expression of many other genes, with 11,350 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FNTA-associated genes across cancer lineages are HOOK3, GOLGA7, and RNF170. Each is linked with FNTA in more than 5 cancer types. Because this analysis shows association rather than direction, both FNTA-to-partner and partner-to-FNTA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FNTA versus HOOK3 in LSCC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNTA→partner) and Y-score (partner→FNTA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HOOK3 →	+0.649	+0.249	<.001	<.001	3	6
BRCA	GOLGA7 →	+0.805	+0.274	<.001	<.001	3	5
BRCA	RNF170 →	+0.634	+0.269	<.001	<.001	3	5
LUAD	HGSNAT →	+0.731	+0.218	<.001	<.001	3	5
HNSC	CLCC1 →	-0.413	-0.224	.001	.001	3	4
LSCC	RNFT2 →	-1.004	-0.207	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,350 associations by consensus.

FNTA vs HOOK3 — LSCC

Explore this scatter interactively →