FNIP2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FNIP2 mutation is significantly associated with the RNA expression of many other genes, with 3,960 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FNIP2-associated genes across cancer lineages are SNRPGP8, RNU6-693P, and RNY1P1. Each is linked with FNIP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FNIP2-to-partner and partner-to-FNIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPGP8 grouped by FNIP2-low versus FNIP2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNIP2→partner) and Y-score (partner→FNIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADSNRPGP8 →+0.213+4.399<.001.00633
COADRNU6-693P →+0.470+4.399<.001.00633
BLCARNY1P1 →+0.210+3.996<.001.00233
BLCARN7SL478P →+0.233+3.098<.001.00733
UCECHIRA →+0.353+2.939.001<.00132
UCECFBXO7 →+0.466+2.786<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,960 associations by consensus.

SNRPGP8 by FNIP2 expression — COAD

Box plot of SNRPGP8 in FNIP2-low vs FNIP2-high samples in COAD.

Explore this box plot interactively →

Exploration