FNIP2

Across TCGA cell cohorts, FNIP2 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FNIP2-associated genes across cancer lineages are HTR3D, CYP39A1, and SFT2D3. Each is linked with FNIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FNIP2-to-partner and partner-to-FNIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HTR3D grouped by FNIP2-low versus FNIP2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNIP2→partner) and Y-score (partner→FNIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	HTR3D →	+0.020	+6.247	<.001	<.001	3	1
BLOOD_Leukemia	CYP39A1 →	+0.198	+3.769	<.001	.008	3	1
BLOOD_Leukemia	SFT2D3 →	+0.725	+4.450	<.001	.001	3	1
BLOOD_Leukemia	PRR30 →	+0.015	+4.269	<.001	.002	3	1
BLOOD_Leukemia	ADGRA1 →	+0.005	+4.786	<.001	<.001	3	1
BLOOD_Leukemia	KRTAP5-1 →	+0.120	+3.855	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

HTR3D by FNIP2 expression — BLOOD_Lymphoma

Explore this box plot interactively →