Across TCGA patient cohorts, FNIP1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,512 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FNIP1-associated genes across cancer lineages are PLAGL2, ANP32B, and POLR1C. Each is linked with FNIP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FNIP1-to-partner and partner-to-FNIP1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNIP1→partner) and Y-score (partner→FNIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PLAGL2 →	-0.778	-0.316	<.001	.001	3	4
LSCC	ANP32B →	-0.484	-0.186	<.001	<.001	3	4
LSCC	POLR1C →	-0.707	-0.355	<.001	<.001	3	4
UCEC	ZBTB24 →	-0.338	-0.232	.001	.004	3	3
LSCC	AAK1 →	-0.547	-0.262	<.001	<.001	3	3
LSCC	PTPN14 →	-0.874	-0.315	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,512 associations by consensus.

Exploration

FNIP1 survival (RNA) · tumor vs normal (RNA) · all FNIP1 data types