FNIP1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FNIP1 mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FNIP1-associated genes across cancer lineages are INPP4B, EGFR_pY1068, and eIF4E. Each is linked with FNIP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FNIP1-to-partner and partner-to-FNIP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNIP1→partner) and Y-score (partner→FNIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECINPP4B →-0.244-1.847.013.00733
UCECEGFR_pY1068 →-0.228-1.700.003.00132
UCECeIF4E →+0.170+1.947.008<.00132
UCECACC1 →+0.235+2.013.034.01632
UCECAcetyl-a-Tubulin-Lys40 →+0.355+1.064.022.04832
UCECJNK_pT183_Y185 →-0.166-2.502.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

Exploration