FNIP1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FNIP1 mutation is significantly associated with the RNA expression of many other genes, with 642 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FNIP1-associated genes across cancer lineages are SLCO1C1, POTEH, and PRAMEF6. Each is linked with FNIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FNIP1-to-partner and partner-to-FNIP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNIP1→partner) and Y-score (partner→FNIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINESLCO1C1 →+0.273+2.242.001.00132
LUNG_NSCLC_LUADPOTEH →+1.004+3.787<.001.00431
LUNG_NSCLC_LUADPRAMEF6 →+0.034+3.362<.001.00731
LUNG_NSCLC_LUADC17orf98 →+0.052+3.882<.001.00331
BLOOD_LymphomaPRKAG3 →+0.358+3.765<.001.00831
BLOOD_LymphomaDMRTB1 →+0.025+3.714<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 642 associations by consensus.

Exploration