FNDC9

Across TCGA patient cohorts, FNDC9 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FNDC9-associated genes across cancer lineages are ASNS, FoxM1, and ACC_pS79. Each is linked with FNDC9 in more than 1 cancer types. Because this analysis shows association rather than direction, both FNDC9-to-partner and partner-to-FNDC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by FNDC9-low versus FNDC9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC9→partner) and Y-score (partner→FNDC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.470	+2.000	.003	.032	3	2
UCEC	FoxM1 →	+0.255	+2.000	.028	.032	3	1
UCEC	ACC_pS79 →	+0.308	+2.000	.049	.032	3	1
UCEC	GAPDH →	+0.522	+2.321	.030	.034	3	1
UCEC	GATA6 →	-0.229	-2.693	.001	.006	3	1
UCEC	Heregulin →	-0.172	-2.986	.002	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

ASNS by FNDC9 expression — UCEC

Explore this box plot interactively →