FNDC7

Across TCGA patient cohorts, FNDC7 mutation is significantly associated with the RNA expression of many other genes, with 2,932 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FNDC7-associated genes across cancer lineages are RNU6-1127P, RNA5SP158, and RNA5SP412. Each is linked with FNDC7 in more than 2 cancer types. Because this analysis shows association rather than direction, both FNDC7-to-partner and partner-to-FNDC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1127P grouped by FNDC7-low versus FNDC7-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC7→partner) and Y-score (partner→FNDC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1127P →	+0.494	+5.721	<.001	.001	3	3
UCEC	RNA5SP158 →	+0.128	+3.242	<.001	.003	3	3
UCEC	RNA5SP412 →	+0.534	+1.967	<.001	.002	3	2
READ	TAS2R9 →	+0.055	+5.421	<.001	.005	3	2
READ	IGHD5-12 →	+1.494	+5.421	<.001	.005	3	2
BRCA	RPL7P40 →	+0.328	+5.153	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,932 associations by consensus.

RNU6-1127P by FNDC7 expression — COAD

Explore this box plot interactively →