FNDC7

Across TCGA cell cohorts, FNDC7 mutation is significantly associated with the mutation status of many other genes, with 4,700 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FNDC7-associated genes across cancer lineages are IGSF9, CELF4, and SEC23IP. Each is linked with FNDC7 in more than 3 cancer types. Because this analysis shows association rather than direction, both FNDC7-to-partner and partner-to-FNDC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGSF9 grouped by FNDC7-low versus FNDC7-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC7→partner) and Y-score (partner→FNDC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	IGSF9 →	+3.655	+4.906	.001	.001	1	4
LUNG_NSCLC_LUAD	CELF4 →	+4.339	+4.339	.009	.009	1	4
BLOOD_Leukemia	SEC23IP →	+4.479	+5.635	<.001	<.001	1	4
LUNG_NSCLC_LUAD	WDR33 →	+3.924	+5.063	.001	.001	1	4
STOMACH	UNC80 →	+3.584	+3.584	.006	.006	1	4
LARGE_INTESTINE	SLC9C1 →	+3.050	+2.736	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,700 associations by consensus.

IGSF9 by FNDC7 expression — SKIN

Explore this box plot interactively →