FNDC4

Across TCGA cell cohorts, FNDC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,028 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FNDC4-associated GO terms across cancer lineages are Maintenance of protein localization in organelle, Protein lipidation, and Endoplasmic reticulum to Golgi vesicle-mediated transport. Each is linked with FNDC4 in more than 11 cancer types. Because this analysis shows association rather than direction, both FNDC4-to-partner and partner-to-FNDC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of protein localization in organelle grouped by FNDC4-low versus FNDC4-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC4→partner) and Y-score (partner→FNDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Maintenance of protein localization in organelle →	+0.069	+1.038	.001	.001	3	12
LARGE_INTESTINE	Protein lipidation →	+0.072	+1.068	<.001	<.001	3	11
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.105	+1.548	.001	<.001	3	10
SKIN	Viral life cycle →	+0.064	+1.172	<.001	<.001	3	9
BREAST	Maintenance of protein location in cell →	+0.117	+1.841	.001	<.001	3	9
BREAST	Maintenance of protein location →	+0.121	+1.814	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,028 associations by consensus.

Maintenance of protein localization in organelle by FNDC4 expression — BREAST

Explore this box plot interactively →