FNDC4

Across TCGA cell cohorts, FNDC4 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FNDC4-associated genes across cancer lineages are SCGB2A1 and HIGD1C. Each is linked with FNDC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FNDC4-to-partner and partner-to-FNDC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB2A1 grouped by FNDC4-low versus FNDC4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC4→partner) and Y-score (partner→FNDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SCGB2A1 →	+0.054	+5.201	<.001	.006	3	1
BLOOD_Leukemia	HIGD1C →	+0.064	+5.201	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SCGB2A1 by FNDC4 expression — BLOOD_Leukemia

Explore this box plot interactively →