Across TCGA pan-cancer cohorts, FNDC3CP RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of FNDC3CP’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where FNDC3CP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FNDC3CP is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.
BRCA, KICH, and KIRC are the cancer types where FNDC3CP tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FNDC3CP RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.