FNDC11

Across TCGA patient cohorts, FNDC11 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FNDC11-associated genes across cancer lineages are Platelets, aDC, and CD8+ T-cells. Each is linked with FNDC11 in more than 1 cancer types. Because this analysis shows association rather than direction, both FNDC11-to-partner and partner-to-FNDC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Platelets grouped by FNDC11-low versus FNDC11-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC11→partner) and Y-score (partner→FNDC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	Platelets →	+0.030	+4.121	<.001	.028	3	2
UCEC	aDC →	+0.103	+3.008	.005	.019	3	1
UCEC	CD8+ T-cells →	+0.023	+2.845	<.001	.005	3	1
UCEC	CD8+ Tcm →	+0.021	+2.350	.030	.031	3	1
UCEC	CD8+ Tem →	+0.003	+4.606	<.001	.044	3	1
UCEC	CD4+ naive T-cells →	+0.017	+3.267	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Platelets by FNDC11 expression — CESC

Explore this box plot interactively →