FNDC11

Across TCGA cell cohorts, FNDC11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,288 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FNDC11-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with FNDC11 in more than 14 cancer types. Because this analysis shows association rather than direction, both FNDC11-to-partner and partner-to-FNDC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by FNDC11-low versus FNDC11-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC11→partner) and Y-score (partner→FNDC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.159	+1.192	.007	.002	2	15
OESOPHAGUS	Regulation of myoblast fusion →	+0.138	+1.192	.007	.002	3	13
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.150	+1.192	.009	.002	2	14
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.133	+1.106	.005	.003	2	13
OESOPHAGUS	Apoptotic signaling pathway →	+0.081	+1.183	<.001	<.001	3	10
OVARY	Regulation of amyloid fibril formation →	+0.141	+0.951	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,288 associations by consensus.

Negative regulation of myoblast fusion by FNDC11 expression — OESOPHAGUS

Explore this box plot interactively →