Across TCGA patient cohorts, FNDC10 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,209 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FNDC10-associated proteins across cancer lineages are SHANK3_S1570, METTL7A, and NSUN5. Each is linked with FNDC10 in more than 3 cancer types. Because this analysis shows association rather than direction, both FNDC10-to-partner and partner-to-FNDC10 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC10→partner) and Y-score (partner→FNDC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SHANK3_S1570 →	-0.692	-0.665	<.001	<.001	3	4
PDAC	METTL7A →	-0.723	-0.512	<.001	<.001	3	4
LSCC	NSUN5 →	+0.246	+0.780	<.001	<.001	3	4
LSCC	PGD →	+0.539	+0.639	<.001	.005	3	4
LSCC	RFC2 →	+0.343	+0.635	<.001	<.001	3	3
PDAC	SH3RF1 →	-0.289	-0.413	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,209 associations by consensus.

Exploration

FNDC10 survival (RNA) · tumor vs normal (RNA) · all FNDC10 data types