FNDC1

Across TCGA pan-cancer cohorts, FNDC1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FNDC1 data layer compared with 19 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher FNDC1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FNDC1 expression acts as an unfavorable survival marker.

PDAC, LSCC, and GBM are the cancer types where FNDC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	IV	0.214	0.785	.006	23	view →
LSCC	DFS	Median	II,III,IV	0.536	0.824	.006	18	view →
GBM	DFS	Median	All	0.663	0.825	.006	12	view →
CCRCC	DFS	Tertile	III,IV	0.224	0.974	.004	10	view →
LUAD	OS	Median	All	0.561	0.837	.012	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FNDC1–PDAC (DFS)

Open the PDAC breakdown →