FNDC1

Across TCGA cell cohorts, FNDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,741 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FNDC1-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Regulation of translational initiation, and Protein-DNA complex assembly. Each is linked with FNDC1 in more than 8 cancer types. Because this analysis shows association rather than direction, both FNDC1-to-partner and partner-to-FNDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by FNDC1-low versus FNDC1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC1→partner) and Y-score (partner→FNDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.117	+0.143	<.001	.006	3	9
OVARY	Regulation of translational initiation →	+0.067	+0.693	.002	.009	3	8
BREAST	Protein-DNA complex assembly →	+0.038	+0.745	.005	.003	3	8
UPPER_AERODIGESTIVE_TRACT	Potassium ion transmembrane transport →	-0.076	-0.176	<.001	.003	3	8
UPPER_AERODIGESTIVE_TRACT	Potassium ion transport →	-0.075	-0.140	<.001	.009	3	7
UPPER_AERODIGESTIVE_TRACT	Calcium ion transport →	-0.069	-0.156	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,741 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by FNDC1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →