Across TCGA pan-cancer cohorts, FNBP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FNBP1 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FNBP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FNBP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, PDAC, and LSCC are the cancer types where FNBP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.854	0.506	<.001	19	view →
PDAC	OS	Tertile	All	0.568	0.279	.008	16	view →
LSCC	OS	Quartile	II,III,IV	0.555	0.927	.012	4	view →
HNSC	OS	Median	III,IV	1.000	0.484	.038	4	view →
CCRCC	DFS	Tertile	II,III,IV	1.000	0.509	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: FNBP1 tumor-vs-normal RNA expression · all FNBP1 data types