FNBP1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FNBP1 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FNBP1-associated genes across cancer lineages are eIF4E, ERK2, and p38-MAPK_pT180_Y182. Each is linked with FNBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FNBP1-to-partner and partner-to-FNBP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNBP1→partner) and Y-score (partner→FNBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECeIF4E →+0.164+2.247.034.00132
UCECERK2 →+0.187+1.502.008.03032
UCECp38-MAPK_pT180_Y182 →-0.424-2.584.010.01032
UCECCaspase-8 →-0.291-3.973.001<.00132
UCEC4E-BP1 →+0.221+2.730.026.00332
UCECEGFR_pY1068 →-0.212-1.502.021.03031
Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration