FN3KRP

Across TCGA pan-cancer cohorts, FN3KRP mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of FN3KRP’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where FN3KRP mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types FN3KRP is over-expressed in tumor, although a few such as COAD and LUAD show the opposite, repressed pattern.

COAD, LUAD, and LSCC are the cancer types where FN3KRP tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FN3KRP mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	II,III,IV	−0.729	<.001	11	view →
LUAD	Female	II,III,IV	−0.384	<.001	9	view →
LSCC	Male	III,IV	−0.407	<.001	8	view →
OV	All	All	−0.381	.034	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

FN3KRP–COAD

Open the COAD breakdown →