FN1

Across TCGA cell cohorts, FN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,449 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FN1-associated GO terms across cancer lineages are Enteric nervous system development, Negative regulation of monocyte activation, and Neural crest cell migration involved in autonomic nervous system development. Each is linked with FN1 in more than 17 cancer types. Because this analysis shows association rather than direction, both FN1-to-partner and partner-to-FN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Enteric nervous system development grouped by FN1-low versus FN1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FN1→partner) and Y-score (partner→FN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Enteric nervous system development →	+0.670	+4.600	.002	<.001	3	18
OESOPHAGUS	Negative regulation of monocyte activation →	+1.651	+4.206	<.001	<.001	3	17
BLOOD_Lymphoma	Neural crest cell migration involved in autonomic nervous system development →	+1.049	+1.931	<.001	.001	3	16
LARGE_INTESTINE	Regulation of substrate-dependent cell migration, cell attachment to substrate →	+0.521	+3.406	<.001	<.001	3	16
LARGE_INTESTINE	Positive regulation of substrate-dependent cell migration, cell attachment to substrate →	+0.521	+3.406	<.001	<.001	3	16
BONE	Protein activation cascade →	+0.409	+4.091	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,449 associations by consensus.

Enteric nervous system development by FN1 expression — OESOPHAGUS

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