FMOD

Across TCGA pan-cancer cohorts, FMOD mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FMOD data layer compared with 27 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher FMOD mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FMOD expression acts as an unfavorable survival marker.

LSCC, CCRCC, and COAD are the cancer types where FMOD mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	0.609	0.912	<.001	57	view →
CCRCC	DFS	Median	III,IV	0.105	0.928	.003	27	view →
COAD	DFS	Median	All	0.885	1.000	.019	12	view →
LUAD	OS	Quartile	II,III,IV	0.524	0.844	.031	7	view →
UCEC	DFS	Tertile	II,III,IV	0.727	1.000	.044	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FMOD–LSCC (OS)

Open the LSCC breakdown →