FMOD

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FMOD protein abundance is significantly associated with the RNA expression of many other genes, with 10,642 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FMOD-associated genes across cancer lineages are MYL9, MEDAG, and GLT8D2. Each is linked with FMOD in more than 8 cancer types. Because this analysis shows association rather than direction, both FMOD-to-partner and partner-to-FMOD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FMOD versus MYL9 in UCEC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMOD→partner) and Y-score (partner→FMOD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMYL9 →+1.629+0.950<.001<.00139
COADMEDAG →+1.243+0.439<.001<.00139
HNSCGLT8D2 →+0.960+0.636<.001<.00139
CCRCCISLR →+1.507+0.766<.001<.00139
UCECCNN1 →+2.042+0.650<.001<.00139
BRCAITGA11 →+1.647+0.859<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,642 associations by consensus.

FMOD vs MYL9 — UCEC

Per-sample scatter of FMOD vs MYL9 in UCEC (Pearson r = 0.48).

Explore this scatter interactively →

Exploration