Across TCGA pan-cancer cohorts, FMO6P Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FMO6P data layer compared with 21 for mass-spec protein and 5 for mass-spec protein.
The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher FMO6P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FMO6P expression acts as an unfavorable survival marker.
CESC are the cancer types where FMO6P Mutation most reproducibly stratifies survival.