FMO6P

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FMO6P mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FMO6P data layer compared with 21 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FMO6P mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FMO6P expression acts as an unfavorable survival marker.

CCRCC, GBM, and HNSC are the cancer types where FMO6P mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSMedianAll0.8531.000.0424view →
GBMDFSTertileAll0.6470.798.0353view →
HNSCOSMedianII,III,IV0.9461.000.0193view →
LUADOSQuartileAll0.6101.000.0252view →
LSCCDFSMedianII,III,IV0.3550.821.0481view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FMO6P–CCRCC (OS)

Kaplan–Meier survival curve for FMO6P mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration