FMO6P

Across TCGA patient cohorts, FMO6P mutation is significantly associated with the RNA expression of many other genes, with 349 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FMO6P-associated genes across cancer lineages are MIR147A, HMGN2P11, and OR9Q2. Each is linked with FMO6P in more than 1 cancer types. Because this analysis shows association rather than direction, both FMO6P-to-partner and partner-to-FMO6P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR147A grouped by FMO6P-low versus FMO6P-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMO6P→partner) and Y-score (partner→FMO6P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR147A →	+0.650	+4.893	<.001	.005	3	2
UCEC	HMGN2P11 →	+0.136	+2.043	.003	.009	3	2
COAD	OR9Q2 →	+0.072	+5.721	<.001	.001	3	2
SARC	FBP2P1 →	+0.086	+5.620	<.001	.004	3	2
UCEC	SLC25A17 →	+0.442	+3.353	.004	.005	3	1
UCEC	MTHFD1 →	+0.568	+3.387	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 349 associations by consensus.

MIR147A by FMO6P expression — COAD

Explore this box plot interactively →