FMO6P

Across TCGA cell cohorts, FMO6P mutation is significantly associated with the mutation status of many other genes, with 1,982 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FMO6P-associated genes across cancer lineages are TNR, KMT2A, and LPIN3. Each is linked with FMO6P in more than 2 cancer types. Because this analysis shows association rather than direction, both FMO6P-to-partner and partner-to-FMO6P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNR grouped by FMO6P-low versus FMO6P-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMO6P→partner) and Y-score (partner→FMO6P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	TNR →	+2.722	+3.906	.004	.004	1	3
OVARY	KMT2A →	+3.562	+4.684	.002	.002	1	3
SKIN	LPIN3 →	+4.053	+4.357	.001	.001	1	3
LARGE_INTESTINE	MYO3B →	+2.152	+2.787	.005	.005	1	3
OVARY	KIAA1549 →	+2.754	+4.095	.009	.009	1	3
OVARY	TNC →	+4.562	+5.217	<.001	<.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,982 associations by consensus.

TNR by FMO6P expression — OESOPHAGUS

Explore this box plot interactively →