FMO4

Across TCGA patient cohorts, FMO4 protein abundance is significantly associated with the RNA expression of many other genes, with 3,517 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FMO4-associated genes across cancer lineages are POLH-AS1, NEFM, and RAB14. Each is linked with FMO4 in more than 2 cancer types. Because this analysis shows association rather than direction, both FMO4-to-partner and partner-to-FMO4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FMO4 versus POLH-AS1 in UCEC, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMO4→partner) and Y-score (partner→FMO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POLH-AS1 →	-1.437	-0.610	.006	.009	3	3
UCEC	NEFM →	-1.920	-0.908	.002	.005	2	3
UCEC	RAB14 →	-0.418	-0.964	.004	.001	3	2
GBM	MAP4K5 →	-0.581	-0.555	.001	<.001	3	2
UCEC	NUSAP1 →	-0.500	-0.616	.004	.002	3	2
UCEC	ABI2 →	-0.750	-0.686	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,517 associations by consensus.

FMO4 vs POLH-AS1 — UCEC

Explore this scatter interactively →