FMO4

Across TCGA patient cohorts, FMO4 mutation is significantly associated with the RNA expression of many other genes, with 1,202 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FMO4-associated genes across cancer lineages are LINC02305, TMEM225, and RNU6-1274P. Each is linked with FMO4 in more than 2 cancer types. Because this analysis shows association rather than direction, both FMO4-to-partner and partner-to-FMO4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02305 grouped by FMO4-low versus FMO4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMO4→partner) and Y-score (partner→FMO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02305 →	+0.069	+2.524	<.001	.007	3	3
READ	TMEM225 →	+0.114	+5.039	<.001	.008	3	2
READ	RNU6-1274P →	+0.547	+5.925	<.001	.002	3	2
UCEC	RN7SL134P →	+0.133	+2.351	<.001	<.001	3	2
SKCM	BORCS8-MEF2B →	+0.319	+2.254	.004	.006	3	2
STAD	MIR654 →	+0.284	+5.226	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,202 associations by consensus.

LINC02305 by FMO4 expression — SKCM

Explore this box plot interactively →