FMO4

Across TCGA cell cohorts, FMO4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,580 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FMO4-associated GO terms across cancer lineages are Lysosomal lumen acidification, Process utilizing autophagic mechanism, and Autophagy. Each is linked with FMO4 in more than 8 cancer types. Because this analysis shows association rather than direction, both FMO4-to-partner and partner-to-FMO4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lysosomal lumen acidification grouped by FMO4-low versus FMO4-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FMO4→partner) and Y-score (partner→FMO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Lysosomal lumen acidification →	+0.140	+1.210	.001	.005	3	9
BREAST	Process utilizing autophagic mechanism →	+0.039	+0.718	.001	.001	2	9
BREAST	Autophagy →	+0.039	+0.718	.001	.001	2	9
BREAST	Vacuolar acidification →	+0.094	+0.621	<.001	.004	3	8
LUNG_SCLC	Endoplasmic reticulum mannose trimming →	+0.083	+0.939	<.001	.001	3	8
LUNG_SCLC	Protein deglycosylation →	+0.126	+0.903	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,580 associations by consensus.

Lysosomal lumen acidification by FMO4 expression — BLOOD_Myeloma

Explore this box plot interactively →