FMO3

Across TCGA patient cohorts, FMO3 protein abundance is significantly associated with the RNA expression of many other genes, with 20,703 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FMO3-associated genes across cancer lineages are DCN, SERPINF1, and LUM. Each is linked with FMO3 in more than 4 cancer types. Because this analysis shows association rather than direction, both FMO3-to-partner and partner-to-FMO3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FMO3 versus DCN in CCRCC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMO3→partner) and Y-score (partner→FMO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	DCN →	+1.729	+0.668	<.001	<.001	3	5
OV	SERPINF1 →	+1.508	+0.772	<.001	<.001	3	5
CCRCC	LUM →	+2.303	+0.692	<.001	<.001	3	5
CCRCC	ABCA8 →	+0.945	+0.804	<.001	<.001	3	5
LSCC	RBMS3 →	+0.583	+1.047	<.001	<.001	3	5
LSCC	ABCA6 →	+0.764	+0.902	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,703 associations by consensus.

FMO3 vs DCN — CCRCC

Explore this scatter interactively →