FMO1

Across TCGA patient cohorts, FMO1 mutation is significantly associated with the RNA expression of many other genes, with 3,131 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FMO1-associated genes across cancer lineages are MIR7-3, MTCO2P23, and NOL12. Each is linked with FMO1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FMO1-to-partner and partner-to-FMO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7-3 grouped by FMO1-low versus FMO1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMO1→partner) and Y-score (partner→FMO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR7-3 →	+0.275	+5.342	<.001	.002	3	4
KIRP	MTCO2P23 →	+0.100	+6.301	<.001	.001	3	3
UCEC	NOL12 →	+0.421	+2.491	<.001	<.001	3	3
UCEC	RNF180 →	-0.976	-3.785	<.001	<.001	3	3
UCEC	CDT1 →	+1.051	+2.970	<.001	<.001	3	3
UCEC	ASNS →	+0.625	+2.233	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,131 associations by consensus.

MIR7-3 by FMO1 expression — CESC

Explore this box plot interactively →