FMNL3

Across TCGA cell cohorts, FMNL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,164 significant associations in total. CNS shows the largest number of these associations.

The most reproducible FMNL3-associated GO terms across cancer lineages are Regulation of telomere maintenance, Regulation of cell-substrate junction assembly, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with FMNL3 in more than 13 cancer types. Because this analysis shows association rather than direction, both FMNL3-to-partner and partner-to-FMNL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance grouped by FMNL3-low versus FMNL3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FMNL3→partner) and Y-score (partner→FMNL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of telomere maintenance →	+0.073	+1.517	<.001	.001	3	14
BREAST	Regulation of cell-substrate junction assembly →	+0.117	+1.212	<.001	<.001	3	13
BREAST	Microtubule cytoskeleton organization involved in mitosis →	+0.077	+0.913	.002	<.001	3	13
LUNG_NSCLC_LUSC	PML body organization →	+0.234	+1.819	<.001	<.001	3	13
SOFT_TISSUE	Host-mediated perturbation of viral process →	+0.059	+1.203	<.001	<.001	3	13
STOMACH	Negative regulation of smoothened signaling pathway →	+0.089	+1.956	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,164 associations by consensus.

Regulation of telomere maintenance by FMNL3 expression — URINARY_TRACT

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