FMNL2

Across TCGA patient cohorts, FMNL2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,471 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FMNL2-associated genes across cancer lineages are NUDCP1, APOE, and MAML3. Each is linked with FMNL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both FMNL2-to-partner and partner-to-FMNL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FMNL2 versus NUDCP1 in HNSC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMNL2→partner) and Y-score (partner→FMNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NUDCP1 →	+1.060	+0.485	.001	<.001	3	7
COAD	APOE →	+1.061	+0.344	.002	<.001	3	6
BRCA	MAML3 →	-0.966	-0.434	<.001	<.001	3	5
BRCA	CTSB →	+0.807	+0.422	<.001	<.001	3	5
BRCA	ARHGAP32 →	-0.700	-0.231	<.001	<.001	3	4
BRCA	ZNF397 →	-0.478	-0.254	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,471 associations by consensus.

FMNL2 vs NUDCP1 — HNSC

Explore this scatter interactively →