FMNL2

Across TCGA cell cohorts, FMNL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,413 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FMNL2-associated GO terms across cancer lineages are Positive regulation of centrosome duplication, Metanephric part of ureteric bud development, and Regulation of atrial cardiac muscle cell membrane depolarization. Each is linked with FMNL2 in more than 7 cancer types. Because this analysis shows association rather than direction, both FMNL2-to-partner and partner-to-FMNL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of centrosome duplication grouped by FMNL2-low versus FMNL2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FMNL2→partner) and Y-score (partner→FMNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of centrosome duplication →	+0.102	+1.002	.002	.002	3	8
BREAST	Metanephric part of ureteric bud development →	+0.806	+1.694	.003	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of atrial cardiac muscle cell membrane depolarization →	+1.273	+1.142	.001	.001	3	8
OVARY	Negative regulation of lysosome organization →	+0.106	+1.163	.007	.001	2	8
UPPER_AERODIGESTIVE_TRACT	Limbic system development →	+0.105	+1.286	<.001	.002	3	7
BREAST	Positive regulation of focal adhesion assembly →	+0.167	+1.989	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,413 associations by consensus.

Positive regulation of centrosome duplication by FMNL2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →