Across TCGA patient cohorts, FMNL1 protein abundance is significantly associated with the RNA expression of many other genes, with 21,539 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FMNL1-associated genes across cancer lineages are CYTH4, NCF4, and CSF2RB. Each is linked with FMNL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both FMNL1-to-partner and partner-to-FMNL1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMNL1→partner) and Y-score (partner→FMNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+1.282	+0.799	<.001	<.001	3	10
GBM	NCF4 →	+1.339	+0.805	<.001	<.001	3	10
GBM	CSF2RB →	+1.295	+0.863	<.001	<.001	3	10
BRCA	IL2RB →	+1.367	+0.479	<.001	<.001	3	10
BRCA	GZMH →	+1.504	+0.499	<.001	<.001	3	10
BRCA	SLA2 →	+1.168	+0.549	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,539 associations by consensus.

Exploration

FMNL1 survival (RNA) · tumor vs normal (RNA) · all FMNL1 data types