Across TCGA cell cohorts, FMNL1 mutation is significantly associated with the RNA expression of many other genes, with 329 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FMNL1-associated genes across cancer lineages are FAM160A1, NEUROG1, and TNMD. Each is linked with FMNL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FMNL1-to-partner and partner-to-FMNL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMNL1→partner) and Y-score (partner→FMNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FAM160A1 →	+0.327	+3.684	<.001	.005	3	2
LUNG_NSCLC_LUAD	NEUROG1 →	+0.024	+4.947	<.001	.001	3	1
LUNG_NSCLC_LUAD	TNMD →	+0.365	+4.371	<.001	.005	3	1
STOMACH	KRTAP4-11 →	+0.020	+5.285	<.001	.003	3	1
STOMACH	TFAP2D →	+0.023	+5.285	<.001	.003	3	1
OVARY	ARMH2 →	+0.052	+4.228	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 329 associations by consensus.

Exploration

FMNL1 survival (RNA) · tumor vs normal (RNA) · all FMNL1 data types