FMN2

Across TCGA patient cohorts, FMN2 mutation is significantly associated with the RNA expression of many other genes, with 6,595 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FMN2-associated genes across cancer lineages are KIF23, CEP55, and OXSR1. Each is linked with FMN2 in more than 5 cancer types. Because this analysis shows association rather than direction, both FMN2-to-partner and partner-to-FMN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIF23 grouped by FMN2-low versus FMN2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMN2→partner) and Y-score (partner→FMN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIF23 →	+0.417	+1.665	.003	.001	3	6
COAD	CEP55 →	+0.496	+2.736	.001	<.001	3	6
STAD	OXSR1 →	+0.421	+2.016	.007	.005	3	5
STAD	EIF5 →	+0.286	+2.781	.007	.002	3	5
STAD	C1orf109 →	+0.334	+2.535	.007	<.001	3	5
UCEC	SAAL1 →	+0.309	+1.716	.003	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,595 associations by consensus.

KIF23 by FMN2 expression — UCEC

Explore this box plot interactively →