FMN2

Across TCGA cell cohorts, FMN2 mutation is significantly associated with the RNA expression of many other genes, with 838 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FMN2-associated genes across cancer lineages are NGLY1, SMU1, and TPPP2. Each is linked with FMN2 in more than 4 cancer types. Because this analysis shows association rather than direction, both FMN2-to-partner and partner-to-FMN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NGLY1 grouped by FMN2-low versus FMN2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMN2→partner) and Y-score (partner→FMN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	NGLY1 →	+0.355	+2.533	.003	.002	3	5
LARGE_INTESTINE	SMU1 →	+0.330	+1.894	.002	.001	3	4
BLOOD_Lymphoma	TPPP2 →	+0.059	+2.794	.007	.007	3	3
LARGE_INTESTINE	RIC8B →	+0.437	+1.808	.001	.001	3	3
LARGE_INTESTINE	MYO5C →	+0.765	+2.000	.003	<.001	3	3
LARGE_INTESTINE	KIF27 →	+0.625	+3.649	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 838 associations by consensus.

NGLY1 by FMN2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →