FLYWCH1

Across TCGA patient cohorts, FLYWCH1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,577 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FLYWCH1-associated genes across cancer lineages are PLD6, WDR54, and RUBCNL. Each is linked with FLYWCH1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FLYWCH1-to-partner and partner-to-FLYWCH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FLYWCH1 versus PLD6 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLYWCH1→partner) and Y-score (partner→FLYWCH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PLD6 →	+0.672	+0.581	<.001	.001	3	3
BRCA	WDR54 →	+0.610	+0.472	.009	.001	3	3
UCEC	RUBCNL →	-0.908	-0.640	.003	<.001	3	3
LSCC	LGMN →	-0.529	-0.443	<.001	<.001	3	2
LSCC	LPXN →	-0.539	-0.303	.001	.006	3	2
BRCA	CHCHD5 →	+0.821	+0.491	.001	.004	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,577 associations by consensus.

FLYWCH1 vs PLD6 — BRCA

Explore this scatter interactively →