FLVCR2

Across TCGA patient cohorts, FLVCR2 mutation is significantly associated with the RNA expression of many other genes, with 4,134 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FLVCR2-associated genes across cancer lineages are CCDC3, ABLIM2, and GPER1. Each is linked with FLVCR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FLVCR2-to-partner and partner-to-FLVCR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC3 grouped by FLVCR2-low versus FLVCR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLVCR2→partner) and Y-score (partner→FLVCR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCDC3 →	-0.673	-2.584	.004	.001	3	2
UCEC	ABLIM2 →	-0.419	-1.716	.005	.004	3	2
UCEC	GPER1 →	-0.619	-2.415	.003	.003	3	2
UCEC	DYNLRB2 →	-0.843	-2.689	.004	.005	3	2
UCEC	LRRC34 →	-0.451	-1.989	.004	.001	3	2
UCEC	EFCAB1 →	-1.078	-3.796	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,134 associations by consensus.

CCDC3 by FLVCR2 expression — UCEC

Explore this box plot interactively →