FLVCR2

Across TCGA patient cohorts, FLVCR2 mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FLVCR2-associated genes across cancer lineages are Caspase-7-cleavedD198, Rictor_pT1135, and ASNS. Each is linked with FLVCR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FLVCR2-to-partner and partner-to-FLVCR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by FLVCR2-low versus FLVCR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLVCR2→partner) and Y-score (partner→FLVCR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.584	+1.926	.006	.008	3	3
UCEC	Rictor_pT1135 →	-0.094	-1.925	.011	.005	3	2
UCEC	ASNS →	+0.443	+2.115	<.001	.016	3	2
UCEC	4E-BP1 →	+0.404	+3.936	<.001	<.001	3	2
BLCA	GSK-3_pS9 →	+0.331	+2.182	.029	.033	3	1
BLCA	GSK-3a-b_pS21_S9 →	+0.341	+2.321	.032	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Caspase-7-cleavedD198 by FLVCR2 expression — UCEC

Explore this box plot interactively →