FLVCR2

Across TCGA cell cohorts, FLVCR2 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FLVCR2-associated genes across cancer lineages are LILRA1, GABRA6, and PTH. Each is linked with FLVCR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FLVCR2-to-partner and partner-to-FLVCR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LILRA1 grouped by FLVCR2-low versus FLVCR2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLVCR2→partner) and Y-score (partner→FLVCR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LILRA1 →	+0.012	+4.510	<.001	.001	3	1
LARGE_INTESTINE	GABRA6 →	+0.447	+3.930	<.001	.003	3	1
LARGE_INTESTINE	PTH →	+0.064	+3.684	<.001	.006	3	1
LARGE_INTESTINE	KLF18 →	+0.009	+3.930	<.001	.003	3	1
BLOOD_Leukemia	ITIH6 →	+0.024	+4.754	<.001	.002	3	1
BLOOD_Leukemia	BRDT →	+0.174	+4.342	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

LILRA1 by FLVCR2 expression — LARGE_INTESTINE

Explore this box plot interactively →