FLVCR1

Across TCGA patient cohorts, FLVCR1 mutation is significantly associated with the RNA expression of many other genes, with 391 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FLVCR1-associated genes across cancer lineages are TOP3A, WRBP1, and LINC02394. Each is linked with FLVCR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FLVCR1-to-partner and partner-to-FLVCR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TOP3A grouped by FLVCR1-low versus FLVCR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLVCR1→partner) and Y-score (partner→FLVCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TOP3A →	+0.576	+2.700	<.001	.006	3	2
CESC	WRBP1 →	+0.308	+4.234	<.001	.008	3	2
CESC	LINC02394 →	+0.083	+4.969	<.001	.004	3	2
HNSC	RAB9BP1 →	+0.075	+5.822	<.001	.003	3	2
HNSC	RN7SL638P →	+0.183	+5.015	<.001	.009	3	2
UCEC	PLPPR2 →	+0.659	+2.711	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 391 associations by consensus.

TOP3A by FLVCR1 expression — UCEC

Explore this box plot interactively →