FLVCR1

Across TCGA patient cohorts, FLVCR1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FLVCR1-associated genes across cancer lineages are HSC, MSC, and Endothelial cells. Each is linked with FLVCR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FLVCR1-to-partner and partner-to-FLVCR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSC grouped by FLVCR1-low versus FLVCR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLVCR1→partner) and Y-score (partner→FLVCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HSC →	+0.110	+2.010	.025	.019	3	2
SKCM	MSC →	-0.193	-3.315	.021	.010	3	1
UCEC	Endothelial cells →	-0.034	-2.657	.047	.006	3	1
ESCA	naive B-cells →	+0.022	+3.218	.001	.045	3	1
SKCM	iDC →	-0.187	-3.315	.025	.010	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

HSC by FLVCR1 expression — UCEC

Explore this box plot interactively →