FLT4

Across TCGA patient cohorts, FLT4 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,403 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FLT4-associated proteins across cancer lineages are CDH5, RASIP1, and NID2. Each is linked with FLT4 in more than 8 cancer types. Because this analysis shows association rather than direction, both FLT4-to-partner and partner-to-FLT4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FLT4 versus CDH5 in BRCA, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FLT4→partner) and Y-score (partner→FLT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDH5 →	+0.653	+0.916	<.001	<.001	3	9
CCRCC	RASIP1 →	+0.684	+1.314	<.001	<.001	3	8
GBM	NID2 →	+0.610	+0.709	<.001	<.001	3	8
CCRCC	MMRN2 →	+0.810	+1.269	<.001	<.001	3	8
CCRCC	CD93 →	+0.652	+0.864	<.001	<.001	3	8
OV	LAMA4 →	+0.637	+0.635	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,403 associations by consensus.

FLT4 vs CDH5 — BRCA

Explore this scatter interactively →