FLT4

Across TCGA patient cohorts, FLT4 protein abundance is significantly associated with the RNA expression of many other genes, with 10,673 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FLT4-associated genes across cancer lineages are DENND1B, LYVE1, and KCNJ15. Each is linked with FLT4 in more than 2 cancer types. Because this analysis shows association rather than direction, both FLT4-to-partner and partner-to-FLT4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FLT4 versus DENND1B in CCRCC, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLT4→partner) and Y-score (partner→FLT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	DENND1B →	-0.472	-0.490	<.001	<.001	3	3
GBM	LYVE1 →	+1.346	+0.683	<.001	<.001	3	3
CCRCC	KCNJ15 →	+1.081	+0.337	.001	.004	3	3
CCRCC	VWA1 →	+0.833	+0.555	<.001	<.001	3	3
GBM	C3orf86 →	+0.379	+0.720	<.001	<.001	3	3
LSCC	FLT1P1 →	+0.331	+0.337	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,673 associations by consensus.

FLT4 vs DENND1B — CCRCC

Explore this scatter interactively →