FLT3

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FLT3 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,227 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FLT3-associated proteins across cancer lineages are EVL, ARHGAP30, and FYB1. Each is linked with FLT3 in more than 9 cancer types. Because this analysis shows association rather than direction, both FLT3-to-partner and partner-to-FLT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FLT3 versus EVL in UCEC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FLT3→partner) and Y-score (partner→FLT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEVL →+0.922+0.852<.001<.001310
HNSCARHGAP30 →+0.693+1.008<.001<.00139
HNSCFYB1 →+0.683+0.845<.001<.00139
HNSCHCLS1 →+0.709+1.015<.001<.00139
HNSCIL16 →+0.765+0.986<.001<.00139
HNSCWAS →+0.584+0.950<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 21,227 associations by consensus.

FLT3 vs EVL — UCEC

Per-sample scatter of FLT3 vs EVL in UCEC (Pearson r = 0.52).

Explore this scatter interactively →

Exploration