FLT3

Across TCGA cell cohorts, FLT3 RNA expression is significantly associated with the RNA expression of many other genes, with 4,453 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FLT3-associated genes across cancer lineages are FCMR, GRIP1, and SPSB4. Each is linked with FLT3 in more than 3 cancer types. Because this analysis shows association rather than direction, both FLT3-to-partner and partner-to-FLT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FLT3 versus FCMR in BLOOD_Lymphoma, with a Pearson correlation of 0.32.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLT3→partner) and Y-score (partner→FLT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	FCMR →	+2.665	+0.367	<.001	.003	3	3
BLOOD_Leukemia	GRIP1 →	+1.869	+2.398	<.001	<.001	3	3
BREAST	SPSB4 →	+0.716	+0.555	<.001	.001	3	3
BREAST	ZNF48 →	+0.987	+0.532	<.001	.004	3	3
BREAST	PGR →	+1.741	+0.591	<.001	.001	2	4
OVARY	GPR27 →	+1.527	+0.470	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,453 associations by consensus.

FLT3 vs FCMR — BLOOD_Lymphoma

Explore this scatter interactively →