FLT1

Across TCGA cell cohorts, FLT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,173 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FLT1-associated GO terms across cancer lineages are COPII-coated vesicle budding, Hyaloid vascular plexus regression, and Regulation of G1/S transition of mitotic cell cycle. Each is linked with FLT1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FLT1-to-partner and partner-to-FLT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle budding grouped by FLT1-low versus FLT1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FLT1→partner) and Y-score (partner→FLT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	COPII-coated vesicle budding →	+0.072	+1.822	.001	.001	3	7
SKIN	Hyaloid vascular plexus regression →	+1.867	+3.524	<.001	<.001	3	7
SKIN	Regulation of G1/S transition of mitotic cell cycle →	+0.057	+2.192	<.001	<.001	3	7
BLOOD_Leukemia	Regulation of nucleotide-excision repair →	+0.091	+1.715	<.001	<.001	3	7
BLOOD_Lymphoma	Negative regulation of gene expression, epigenetic →	+0.055	+1.331	<.001	<.001	3	7
BLOOD_Lymphoma	Heterochromatin formation →	+0.055	+1.163	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,173 associations by consensus.

COPII-coated vesicle budding by FLT1 expression — SOFT_TISSUE

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